C1QL2

Across TCGA cell cohorts, C1QL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 655 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C1QL2-associated GO terms across cancer lineages are Cytoplasmic translational initiation, Positive regulation of lyase activity, and Purine nucleotide biosynthetic process. Each is linked with C1QL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both C1QL2-to-partner and partner-to-C1QL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translational initiation grouped by C1QL2-low versus C1QL2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QL2→partner) and Y-score (partner→C1QL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cytoplasmic translational initiation →	+0.097	+1.151	<.001	.001	3	3
LUNG_SCLC	Positive regulation of lyase activity →	-0.122	-0.768	.001	.003	3	3
LUNG_SCLC	Purine nucleotide biosynthetic process →	+0.047	+0.593	.003	.009	3	3
LUNG_SCLC	Cellular response to mechanical stimulus →	-0.068	-0.684	.009	.008	3	3
LUNG_SCLC	Cellular response to external stimulus →	-0.067	-0.684	.009	.008	3	3
BONE	Negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell →	-1.207	-1.239	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 655 associations by consensus.

Cytoplasmic translational initiation by C1QL2 expression — LUNG_SCLC

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