C1QC

Across TCGA patient cohorts, C1QC RNA expression is significantly associated with the protein abundance of many other proteins, with 21,955 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1QC-associated proteins across cancer lineages are TYMP, RCSD1, and SKAP2. Each is linked with C1QC in more than 9 cancer types. Because this analysis shows association rather than direction, both C1QC-to-partner and partner-to-C1QC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C1QC versus TYMP in GBM, with a Pearson correlation of 0.83.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QC→partner) and Y-score (partner→C1QC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TYMP →	+0.953	+1.331	<.001	<.001	3	10
HNSC	RCSD1 →	+0.774	+1.208	<.001	.001	3	10
GBM	SKAP2 →	+0.896	+1.505	<.001	<.001	3	10
OV	THEMIS2_T593 →	+0.773	+1.100	.001	<.001	3	10
GBM	TRPM2_S38 →	+0.927	+1.327	<.001	<.001	3	10
HNSC	WARS1 →	+0.825	+1.024	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,955 associations by consensus.

C1QC vs TYMP — GBM

Explore this scatter interactively →