C1QB

Across TCGA pan-cancer cohorts, C1QB Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C1QB data layer compared with 23 for mass-spec protein and 8 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher C1QB Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C1QB expression acts as an unfavorable survival marker.

ESCA, SARC, and PRAD are the cancer types where C1QB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.074	0.703	<.001	48	view →
SARC	DFS	Median	All	0.121	0.611	.041	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C1QB–ESCA (OS)

Open the ESCA breakdown →