C1QB

Across TCGA patient cohorts, C1QB mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C1QB-associated genes across cancer lineages are Eosinophils, Class-switched memory B-cells, and Hepatocytes. Each is linked with C1QB in more than 1 cancer types. Because this analysis shows association rather than direction, both C1QB-to-partner and partner-to-C1QB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by C1QB-low versus C1QB-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1QB→partner) and Y-score (partner→C1QB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Eosinophils →	+0.069	+2.472	<.001	.032	3	2
UCEC	Class-switched memory B-cells →	-0.054	-3.044	.037	.014	3	1
SKCM	Hepatocytes →	-0.016	-2.315	.028	.036	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Eosinophils by C1QB expression — LUAD

Explore this box plot interactively →