Across TCGA pan-cancer cohorts, C1GALT1C1L RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated C1GALT1C1L data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher C1GALT1C1L RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C1GALT1C1L expression acts as an unfavorable survival marker, although some lineages such as THYM and UCS show a favorable association.

STAD, ACC, and LGG are the cancer types where C1GALT1C1L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Quartile	All	0.361	0.622	.003	60	view →
ACC	DFS	Median	All	0.411	0.754	<.001	49	view →
LGG	DFS	Median	All	0.678	0.795	<.001	41	view →
UVM	OS	Tertile	All	0.610	1.000	.022	33	view →
COAD	DFS	Median	All	0.597	0.769	.004	24	view →
THYM	DFS	Median	All	0.966	0.748	.005	21	view →
UCS	DFS	Median	II,III,IV	0.484	0.137	.007	18	view →
LUAD	DFS	Quartile	All	0.848	0.676	.003	16	view →
BRCA	OS	Tertile	III,IV	0.939	0.838	.008	13	view →
READ	DFS	Tertile	IV	0.312	0.815	.001	12	view →
UCEC	DFS	Quartile	All	0.795	0.878	.018	12	view →
KIRC	DFS	Median	III,IV	0.583	0.276	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

Exploration

Same gene, other analysis: C1GALT1C1L tumor-vs-normal RNA expression · all C1GALT1C1L data types