C1GALT1

Across TCGA patient cohorts, C1GALT1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C1GALT1-associated genes across cancer lineages are ASNS, VHL, and PDCD4. Each is linked with C1GALT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both C1GALT1-to-partner and partner-to-C1GALT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by C1GALT1-low versus C1GALT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C1GALT1→partner) and Y-score (partner→C1GALT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.479	+3.321	.006	.010	3	2
UCEC	VHL →	-0.876	-3.169	.007	.019	3	1
UCEC	PDCD4 →	-0.654	-2.990	.004	.036	2	1
UCEC	Rad50 →	-0.391	-3.584	<.001	.002	2	1
UCEC	TFRC →	+0.674	+3.169	.008	.019	2	1
UCEC	EGFR_pY1068 →	-0.276	-3.584	.022	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ASNS by C1GALT1 expression — UCEC

Explore this box plot interactively →