Across TCGA patient cohorts, C1D RNA expression is significantly associated with the protein abundance of many other proteins, with 13,650 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C1D-associated proteins across cancer lineages are NCKAP1L, UTP25, and BIN2_S444. Each is linked with C1D in more than 3 cancer types. Because this analysis shows association rather than direction, both C1D-to-partner and partner-to-C1D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C1D→partner) and Y-score (partner→C1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NCKAP1L →	-0.407	-0.523	<.001	<.001	3	4
UCEC	UTP25 →	+0.393	+0.622	<.001	.003	3	4
HNSC	BIN2_S444 →	-0.909	-0.701	<.001	.003	3	4
LSCC	PSME4 →	+0.242	+0.349	<.001	<.001	3	4
LSCC	GLCCI1_S145 →	-0.617	-0.598	<.001	<.001	3	4
LSCC	NOL10 →	+0.356	+0.550	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,650 associations by consensus.

Exploration

C1D survival (RNA) · tumor vs normal (RNA) · all C1D data types