C19orf84

Across TCGA pan-cancer cohorts, C19orf84 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated C19orf84 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher C19orf84 RNA is associated with better overall survival. In most high-consensus cancer types, elevated C19orf84 expression acts as an unfavorable survival marker, although some lineages such as CESC and SKCM show a favorable association.

CESC, BLCA, and KIRC are the cancer types where C19orf84 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	III,IV	0.912	0.596	.005	54	view →
BLCA	DFS	Quartile	II,III,IV	0.504	0.669	.002	54	view →
KIRC	DFS	Quartile	IV	0.215	0.549	.001	48	view →
LGG	DFS	Median	All	0.665	0.809	<.001	45	view →
LAML	DFS	Median	All	0.267	0.483	.003	36	view →
LIHC	OS	Quartile	II,III,IV	0.473	0.766	.004	25	view →
SKCM	OS	Median	All	0.417	0.269	<.001	24	view →
LUAD	OS	Median	All	0.232	0.536	.002	21	view →
GBM	DFS	Tertile	All	0.206	0.466	.006	18	view →
UCEC	OS	Quartile	All	0.823	0.911	.010	18	view →
STAD	DFS	Tertile	All	0.568	0.696	.012	14	view →
THCA	DFS	Tertile	All	0.883	0.745	.004	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

C19orf84–CESC (OS)

Open the CESC breakdown →