Across TCGA patient cohorts, C19orf54 mutation is significantly associated with the RNA expression of many other genes, with 1,474 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C19orf54-associated genes across cancer lineages are RNA5SP420, CRYGA, and LCEP1. Each is linked with C19orf54 in more than 2 cancer types. Because this analysis shows association rather than direction, both C19orf54-to-partner and partner-to-C19orf54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf54→partner) and Y-score (partner→C19orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP420 →	+0.673	+2.552	<.001	.002	3	3
BLCA	CRYGA →	+0.094	+4.497	<.001	.009	3	2
BRCA	LCEP1 →	+0.157	+5.268	<.001	.003	3	2
BRCA	RN7SL223P →	+0.119	+5.866	<.001	.001	3	2
UCEC	RNA5SP411 →	+1.073	+2.393	.001	.002	3	2
UCEC	RNA5SP412 →	+0.730	+2.552	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,474 associations by consensus.

Exploration

C19orf54 survival (RNA) · tumor vs normal (RNA) · all C19orf54 data types