C19orf53

Across TCGA patient cohorts, C19orf53 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,117 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C19orf53-associated proteins across cancer lineages are DNAJB1, TRMT1, and NR2C2AP. Each is linked with C19orf53 in more than 5 cancer types. Because this analysis shows association rather than direction, both C19orf53-to-partner and partner-to-C19orf53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C19orf53 versus DNAJB1 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf53→partner) and Y-score (partner→C19orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNAJB1 →	+0.592	+0.785	<.001	<.001	3	6
LSCC	TRMT1 →	+0.292	+0.432	<.001	<.001	3	6
LSCC	NR2C2AP →	+0.378	+0.452	<.001	<.001	3	5
LSCC	WDR43 →	+0.491	+0.473	<.001	<.001	3	4
LSCC	SDF2L1 →	-0.408	-0.441	<.001	<.001	3	4
HNSC	CRELD2 →	-0.486	-0.945	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,117 associations by consensus.

C19orf53 vs DNAJB1 — OV

Explore this scatter interactively →