C19orf53

Across TCGA patient cohorts, C19orf53 protein abundance is significantly associated with the RNA expression of many other genes, with 9,143 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C19orf53-associated genes across cancer lineages are SCN7A, MS4A2, and SIGLEC6. Each is linked with C19orf53 in more than 5 cancer types. Because this analysis shows association rather than direction, both C19orf53-to-partner and partner-to-C19orf53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C19orf53 versus SCN7A in LUAD, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf53→partner) and Y-score (partner→C19orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SCN7A →	+1.288	+0.574	<.001	<.001	3	6
BRCA	MS4A2 →	+0.909	+0.476	.001	.003	3	6
LUAD	SIGLEC6 →	+0.780	+0.513	<.001	<.001	3	5
HNSC	ABCA9 →	+0.872	+0.407	<.001	<.001	3	5
LSCC	SIGLEC17P →	+0.727	+0.588	<.001	<.001	3	5
BRCA	ACKR1 →	+1.114	+0.361	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,143 associations by consensus.

C19orf53 vs SCN7A — LUAD

Explore this scatter interactively →