C19orf48

Across TCGA pan-cancer cohorts, C19orf48 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C19orf48 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher C19orf48 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C19orf48 expression acts as an unfavorable survival marker.

OV, LGG, and LUSC are the cancer types where C19orf48 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.346	0.843	.003	18	view →
LGG	OS	Median	All	0.250	0.830	.001	12	view →
LUSC	OS	Median	III,IV	0.126	0.664	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C19orf48–OV (OS)

Open the OV breakdown →