C19orf25

Across TCGA pan-cancer cohorts, C19orf25 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated C19orf25 data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher C19orf25 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated C19orf25 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, UCEC, and CCRCC are the cancer types where C19orf25 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.886	.020	36	view →
UCEC	DFS	Quartile	All	0.978	0.781	.016	34	view →
CCRCC	DFS	Quartile	All	0.886	0.539	.001	25	view →
GBM	DFS	Median	All	0.465	0.288	.020	12	view →
PDAC	OS	Median	All	0.613	0.463	.005	4	view →
HNSC	DFS	Median	III,IV	0.495	0.716	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

C19orf25–COAD (DFS)

Open the COAD breakdown →