C19orf25

Across TCGA patient cohorts, C19orf25 protein abundance is significantly associated with the RNA expression of many other genes, with 10,357 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C19orf25-associated genes across cancer lineages are PPP1R3D, HSP90AB1, and ZNF706. Each is linked with C19orf25 in more than 3 cancer types. Because this analysis shows association rather than direction, both C19orf25-to-partner and partner-to-C19orf25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C19orf25 versus PPP1R3D in COAD, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf25→partner) and Y-score (partner→C19orf25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PPP1R3D →	-0.523	-0.158	<.001	<.001	3	4
LSCC	HSP90AB1 →	-0.567	-0.172	.004	<.001	3	4
BRCA	ZNF706 →	-0.491	-0.220	<.001	<.001	3	4
LUAD	SINHCAF →	-0.619	-0.165	<.001	.001	3	4
BRCA	RAD21 →	-0.622	-0.207	.005	<.001	3	4
LSCC	MTBP →	-0.522	-0.128	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,357 associations by consensus.

C19orf25 vs PPP1R3D — COAD

Explore this scatter interactively →