C19orf25

Across TCGA cell cohorts, C19orf25 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C19orf25-associated genes across cancer lineages are CGB5, TLE7, and SMR3B. Each is linked with C19orf25 in more than 1 cancer types. Because this analysis shows association rather than direction, both C19orf25-to-partner and partner-to-C19orf25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CGB5 grouped by C19orf25-low versus C19orf25-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf25→partner) and Y-score (partner→C19orf25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CGB5 →	+0.083	+4.409	<.001	.005	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
LARGE_INTESTINE	SMR3B →	+0.968	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CGB5 by C19orf25 expression — BLOOD_Leukemia

Explore this box plot interactively →