C19orf12

Across TCGA patient cohorts, C19orf12 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,603 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C19orf12-associated proteins across cancer lineages are RPS8_T130, TBCB, and PLEKHF1. Each is linked with C19orf12 in more than 4 cancer types. Because this analysis shows association rather than direction, both C19orf12-to-partner and partner-to-C19orf12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C19orf12 versus RPS8_T130 in HNSC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf12→partner) and Y-score (partner→C19orf12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPS8_T130 →	-0.651	-0.507	<.001	<.001	3	4
UCEC	TBCB →	+0.391	+0.479	<.001	.008	3	4
OV	PLEKHF1 →	+0.567	+0.882	<.001	.002	2	5
LSCC	MYEF2 →	+0.869	+0.531	<.001	<.001	3	4
BRCA	ILK →	+0.327	+0.549	.004	<.001	3	4
PDAC	FAM168A →	+0.609	+0.218	.004	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,603 associations by consensus.

C19orf12 vs RPS8_T130 — HNSC

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