C19orf12

Across TCGA patient cohorts, C19orf12 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C19orf12-associated genes across cancer lineages are GMP, Chondrocytes, and Adipocytes. Each is linked with C19orf12 in more than 1 cancer types. Because this analysis shows association rather than direction, both C19orf12-to-partner and partner-to-C19orf12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by C19orf12-low versus C19orf12-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C19orf12→partner) and Y-score (partner→C19orf12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.057	+3.264	.001	.046	3	1
UCEC	Chondrocytes →	+0.010	+2.149	<.001	.011	3	1
UCEC	Adipocytes →	+0.019	+1.681	.013	.040	3	1
UCEC	Mesangial cells →	+0.036	+2.233	.033	.031	3	1
UCEC	Class-switched memory B-cells →	-0.053	-2.181	.034	.043	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GMP by C19orf12 expression — LUSC

Explore this box plot interactively →