C18orf54

Across TCGA cell cohorts, C18orf54 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,843 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C18orf54-associated GO terms across cancer lineages are Mitotic chromosome condensation, Centrosome cycle, and Microtubule organizing center organization. Each is linked with C18orf54 in more than 17 cancer types. Because this analysis shows association rather than direction, both C18orf54-to-partner and partner-to-C18orf54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by C18orf54-low versus C18orf54-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf54→partner) and Y-score (partner→C18orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic chromosome condensation →	+0.259	+0.873	<.001	<.001	3	18
OESOPHAGUS	Centrosome cycle →	+0.122	+0.932	<.001	<.001	3	18
OESOPHAGUS	Microtubule organizing center organization →	+0.119	+0.981	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.075	+0.748	<.001	<.001	3	18
OESOPHAGUS	Nuclear division →	+0.151	+1.003	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Spindle assembly →	+0.089	+0.840	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,843 associations by consensus.

Mitotic chromosome condensation by C18orf54 expression — OESOPHAGUS

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