C18orf25

Across TCGA patient cohorts, C18orf25 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,255 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C18orf25-associated proteins across cancer lineages are SMAD4, CTDP1, and VRK1. Each is linked with C18orf25 in more than 7 cancer types. Because this analysis shows association rather than direction, both C18orf25-to-partner and partner-to-C18orf25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C18orf25 versus SMAD4 in LUAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf25→partner) and Y-score (partner→C18orf25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SMAD4 →	+0.318	+0.594	<.001	<.001	2	8
LSCC	CTDP1 →	+0.238	+0.507	<.001	<.001	3	6
LSCC	VRK1 →	+0.606	+0.559	<.001	<.001	3	5
LSCC	TXNL1 →	+0.376	+0.630	<.001	<.001	3	5
LUAD	C18orf25_S145 →	+0.457	+0.511	.003	.004	3	5
BRCA	RPRD1A →	+0.432	+0.639	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,255 associations by consensus.

C18orf25 vs SMAD4 — LUAD

Explore this scatter interactively →