C18orf25

Across TCGA patient cohorts, C18orf25 protein abundance is significantly associated with the RNA expression of many other genes, with 14,407 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C18orf25-associated genes across cancer lineages are C18orf21, HAUS1, and TXNL1. Each is linked with C18orf25 in more than 5 cancer types. Because this analysis shows association rather than direction, both C18orf25-to-partner and partner-to-C18orf25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C18orf25 versus C18orf21 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf25→partner) and Y-score (partner→C18orf25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C18orf21 →	+0.540	+0.470	<.001	<.001	3	6
OV	HAUS1 →	+0.628	+0.517	.002	<.001	3	6
LSCC	TXNL1 →	+0.610	+0.417	<.001	<.001	3	6
OV	CEP72 →	+0.798	+0.354	<.001	.005	3	5
LSCC	AFG3L2 →	+0.573	+0.271	<.001	<.001	3	5
OV	RPRD1A →	+0.715	+0.509	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,407 associations by consensus.

C18orf25 vs C18orf21 — OV

Explore this scatter interactively →