C18orf25

Across TCGA patient cohorts, C18orf25 mutation is significantly associated with the RNA expression of many other genes, with 1,081 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C18orf25-associated genes across cancer lineages are RN7SKP245, RNU6-289P, and RNA5SP408. Each is linked with C18orf25 in more than 1 cancer types. Because this analysis shows association rather than direction, both C18orf25-to-partner and partner-to-C18orf25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP245 grouped by C18orf25-low versus C18orf25-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf25→partner) and Y-score (partner→C18orf25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP245 →	+0.096	+4.812	<.001	.006	3	2
BLCA	RNU6-289P →	+0.255	+4.899	<.001	.005	3	2
LUAD	RNA5SP408 →	+0.308	+7.930	<.001	.008	3	2
COAD	OR11H6 →	+0.070	+5.435	.004	.005	3	2
UCEC	RNU1-17P →	+0.182	+2.198	<.001	.003	3	2
UCEC	RN7SKP132 →	+0.062	+2.938	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,081 associations by consensus.

RN7SKP245 by C18orf25 expression — CESC

Explore this box plot interactively →