C18orf21

Across TCGA patient cohorts, C18orf21 protein abundance is significantly associated with the RNA expression of many other genes, with 2,747 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C18orf21-associated genes across cancer lineages are LONRF3, CSRP3-AS1, and SLC9B2. Each is linked with C18orf21 in more than 2 cancer types. Because this analysis shows association rather than direction, both C18orf21-to-partner and partner-to-C18orf21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C18orf21 versus LONRF3 in UCEC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf21→partner) and Y-score (partner→C18orf21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LONRF3 →	-0.911	-0.251	<.001	.003	3	3
COAD	CSRP3-AS1 →	-0.645	-0.531	.002	.004	3	2
BRCA	SLC9B2 →	-0.512	-0.437	.002	<.001	3	2
LUAD	NUBP1 →	-0.296	-0.292	<.001	.007	3	2
GBM	KCNJ3 →	-1.154	-0.335	.007	.004	3	2
LUAD	ZNRF2 →	-0.418	-0.386	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,747 associations by consensus.

C18orf21 vs LONRF3 — UCEC

Explore this scatter interactively →