C18orf21

Across TCGA cell cohorts, C18orf21 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,813 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C18orf21-associated GO terms across cancer lineages are Cellular response to low-density lipoprotein particle stimulus, Response to retinoic acid, and Cell-substrate adhesion. Each is linked with C18orf21 in more than 8 cancer types. Because this analysis shows association rather than direction, both C18orf21-to-partner and partner-to-C18orf21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to low-density lipoprotein particle stimulus grouped by C18orf21-low versus C18orf21-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C18orf21→partner) and Y-score (partner→C18orf21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cellular response to low-density lipoprotein particle stimulus →	-0.130	-0.870	.005	.004	3	8
LUNG_NSCLC_LUAD	Response to retinoic acid →	-0.079	-0.875	<.001	<.001	3	8
STOMACH	Cell-substrate adhesion →	-0.106	-0.576	.002	.001	3	8
OESOPHAGUS	Response to lipoprotein particle →	-0.130	-0.870	.005	.004	3	8
LUNG_SCLC	RNA capping →	+0.064	+0.372	<.001	.006	3	8
OESOPHAGUS	Cerebral cortex radially oriented cell migration →	-0.157	-0.943	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,813 associations by consensus.

Cellular response to low-density lipoprotein particle stimulus by C18orf21 expression — OESOPHAGUS

Explore this box plot interactively →