Across TCGA patient cohorts, C17orf99 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf99-associated genes across cancer lineages are p27, VHL, and Di-Ras3. Each is linked with C17orf99 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf99-to-partner and partner-to-C17orf99 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf99→partner) and Y-score (partner→C17orf99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27 →	+0.358	+2.999	.001	.035	3	1
UCEC	VHL →	-0.863	-2.321	.011	.034	3	1
UCEC	Di-Ras3 →	-0.167	-2.321	.025	.035	3	1
UCEC	INPP4B →	-0.374	-3.446	.021	.005	1	1
UCEC	Caspase-8 →	-0.269	-2.321	.033	.035	1	1
UCEC	c-Myc →	-0.252	-3.446	.041	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

C17orf99 survival (RNA) · tumor vs normal (RNA) · all C17orf99 data types