C17orf98

Across TCGA patient cohorts, C17orf98 mutation is significantly associated with the RNA expression of many other genes, with 480 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf98-associated genes across cancer lineages are RNU6-40P, PER1, and RNU6-1082P. Each is linked with C17orf98 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf98-to-partner and partner-to-C17orf98 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-40P grouped by C17orf98-low versus C17orf98-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf98→partner) and Y-score (partner→C17orf98) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-40P →	+0.459	+4.537	<.001	.006	3	2
UCEC	PER1 →	+0.590	+3.364	.003	.004	3	2
UCEC	RNU6-1082P →	+0.177	+2.644	.001	.005	3	2
SKCM	RN7SL835P →	+0.140	+3.368	<.001	.002	3	2
SKCM	RETNLB →	+0.170	+3.057	<.001	.005	3	1
SKCM	MIR6499 →	+0.260	+4.039	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 480 associations by consensus.

RNU6-40P by C17orf98 expression — COAD

Explore this box plot interactively →