C17orf98

Across TCGA patient cohorts, C17orf98 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf98-associated genes across cancer lineages are Myosin-IIa, Rad50, and Tuberin. Each is linked with C17orf98 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf98-to-partner and partner-to-C17orf98 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa grouped by C17orf98-low versus C17orf98-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf98→partner) and Y-score (partner→C17orf98) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myosin-IIa →	+0.153	+3.010	.045	.019	3	1
UCEC	Rad50 →	-0.245	-1.807	.014	.027	2	2
UCEC	Tuberin →	+0.254	+1.807	.022	.027	3	1
UCEC	ATM →	-0.504	-2.459	.007	.019	3	1
UCEC	Caspase-8 →	-0.226	-3.295	.029	.009	3	1
UCEC	Claudin-7 →	-0.451	-1.807	.030	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Myosin-IIa by C17orf98 expression — UCEC

Explore this box plot interactively →