C17orf98

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C17orf98 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible C17orf98-associated genes across cancer lineages are PTH and C7orf77. Each is linked with C17orf98 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf98-to-partner and partner-to-C17orf98 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH grouped by C17orf98-low versus C17orf98-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf98→partner) and Y-score (partner→C17orf98) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADPTH →+0.020+4.887.005.00931
LUNG_NSCLC_LUADC7orf77 →+0.034+5.662.001.00231
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PTH by C17orf98 expression — LUNG_NSCLC_LUAD

Box plot of PTH in C17orf98-low vs C17orf98-high samples in LUNG_NSCLC_LUAD.

Explore this box plot interactively →

Exploration