C17orf97

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C17orf97 mutation is significantly associated with the RNA expression of many other genes, with 468 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf97-associated genes across cancer lineages are SKA1, EOMES, and MRM3. Each is linked with C17orf97 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf97-to-partner and partner-to-C17orf97 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf97→partner) and Y-score (partner→C17orf97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSKA1 →+0.745+2.609<.001.00532
UCECEOMES →+0.684+3.470<.001.00232
UCECMRM3 →+0.387+3.480.008.00232
UCECRAD51 →+0.781+3.010<.001<.00132
UCECHACD3 →+0.622+2.716.006.00332
UCECITGAE →+0.447+2.716.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 468 associations by consensus.

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