Across TCGA patient cohorts, C17orf97 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf97-associated genes across cancer lineages are eIF4E, Caspase-7-cleavedD198, and p62 Lck ligand. Each is linked with C17orf97 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf97-to-partner and partner-to-C17orf97 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf97→partner) and Y-score (partner→C17orf97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eIF4E →	+0.286	+2.832	.003	.035	3	2
COAD	Caspase-7-cleavedD198 →	+1.500	+2.824	<.001	.034	3	2
UCEC	p62 Lck ligand →	+0.327	+2.009	.015	.017	3	2
COAD	eEF2 →	+0.662	+2.815	<.001	.036	3	1
UCEC	MEK1 →	+0.446	+1.807	.003	.027	2	2
UCEC	EGFR →	-0.178	-1.807	.007	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

C17orf97 survival (RNA) · tumor vs normal (RNA) · all C17orf97 data types