C17orf78

Across TCGA cell cohorts, C17orf78 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,871 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C17orf78-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Negative regulation of chromosome condensation, and Regulatory ncRNA processing. Each is linked with C17orf78 in more than 6 cancer types. Because this analysis shows association rather than direction, both C17orf78-to-partner and partner-to-C17orf78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by C17orf78-low versus C17orf78-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf78→partner) and Y-score (partner→C17orf78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Viral translational termination-reinitiation →	+0.067	+0.050	<.001	<.001	3	7
BREAST	Negative regulation of chromosome condensation →	+0.081	+0.042	.003	.002	3	7
BLOOD_Leukemia	Regulatory ncRNA processing →	+0.031	+0.037	.009	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of T-helper 17 cell lineage commitment →	+0.160	+0.044	<.001	.002	3	6
BLOOD_Leukemia	Microtubule polymerization →	+0.082	+0.049	<.001	<.001	3	6
CNS	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.099	+0.044	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,871 associations by consensus.

Viral translational termination-reinitiation by C17orf78 expression — BLOOD_Leukemia

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