C17orf64

Across TCGA patient cohorts, C17orf64 mutation is significantly associated with the RNA expression of many other genes, with 2,358 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf64-associated genes across cancer lineages are TPMTP3, XPNPEP1, and MLX. Each is linked with C17orf64 in more than 2 cancer types. Because this analysis shows association rather than direction, both C17orf64-to-partner and partner-to-C17orf64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPMTP3 grouped by C17orf64-low versus C17orf64-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf64→partner) and Y-score (partner→C17orf64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TPMTP3 →	+0.034	+3.594	<.001	<.001	3	3
SKCM	XPNPEP1 →	+0.510	+3.468	.004	.002	3	2
UCEC	MLX →	+0.506	+2.463	<.001	.001	3	2
UCEC	TCF19 →	+0.719	+3.595	.001	.001	3	2
LUAD	PRELID3BP1 →	+0.167	+3.855	<.001	.006	3	2
LUAD	LINC01162 →	+0.680	+3.659	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,358 associations by consensus.

TPMTP3 by C17orf64 expression — SKCM

Explore this box plot interactively →