C17orf50

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C17orf50 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C17orf50-associated genes across cancer lineages are KRTAP10-1 and OR5V1. Each is linked with C17orf50 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf50-to-partner and partner-to-C17orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-1 grouped by C17orf50-low versus C17orf50-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf50→partner) and Y-score (partner→C17orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEKRTAP10-1 →+0.009+4.415<.001.00731
LARGE_INTESTINEOR5V1 →+0.010+5.022<.001.00231
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KRTAP10-1 by C17orf50 expression — LARGE_INTESTINE

Box plot of KRTAP10-1 in C17orf50-low vs C17orf50-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration