C17orf50

Across TCGA cell cohorts, C17orf50 mutation is significantly associated with the mutation status of many other genes, with 246 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C17orf50-associated genes across cancer lineages are ARMCX1, BRS3, and PPM1G. Each is linked with C17orf50 in more than 2 cancer types. Because this analysis shows association rather than direction, both C17orf50-to-partner and partner-to-C17orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARMCX1 grouped by C17orf50-low versus C17orf50-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf50→partner) and Y-score (partner→C17orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARMCX1 →	+3.350	+4.584	.003	.003	1	3
LARGE_INTESTINE	BRS3 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	PPM1G →	+2.865	+4.217	.007	.007	1	2
LARGE_INTESTINE	CSE1L →	+3.350	+4.584	.003	.003	1	2
LARGE_INTESTINE	SEPTIN11 →	+3.672	+4.799	.002	.002	1	2
LARGE_INTESTINE	MBOAT2 →	+3.350	+4.584	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 246 associations by consensus.

ARMCX1 by C17orf50 expression — LARGE_INTESTINE

Explore this box plot interactively →