C17orf49

Across TCGA cell cohorts, C17orf49 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,619 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C17orf49-associated GO terms across cancer lineages are Telomere assembly, Postsynaptic density protein 95 clustering, and Heme A biosynthetic process. Each is linked with C17orf49 in more than 11 cancer types. Because this analysis shows association rather than direction, both C17orf49-to-partner and partner-to-C17orf49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by C17orf49-low versus C17orf49-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf49→partner) and Y-score (partner→C17orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Telomere assembly →	+0.151	+0.758	<.001	<.001	3	12
URINARY_TRACT	Postsynaptic density protein 95 clustering →	+1.290	+0.888	<.001	<.001	3	10
URINARY_TRACT	Heme A biosynthetic process →	+0.101	+0.676	.001	.004	3	9
OVARY	Regulation of establishment of protein localization to chromosome →	+0.095	+0.824	<.001	<.001	3	9
URINARY_TRACT	Regulation of telomere maintenance via telomerase →	+0.074	+1.140	<.001	<.001	3	9
URINARY_TRACT	Locomotory exploration behavior →	+0.232	+0.954	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,619 associations by consensus.

Telomere assembly by C17orf49 expression — LUNG_SCLC

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