C17orf113

Across TCGA cell cohorts, C17orf113 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,242 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C17orf113-associated GO terms across cancer lineages are Negative regulation of proteasomal ubiquitin-dependent protein catabolic process, Regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with C17orf113 in more than 15 cancer types. Because this analysis shows association rather than direction, both C17orf113-to-partner and partner-to-C17orf113 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of proteasomal ubiquitin-dependent protein catabolic process grouped by C17orf113-low versus C17orf113-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf113→partner) and Y-score (partner→C17orf113) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.103	+0.762	<.001	.001	3	16
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.122	+0.900	.003	<.001	2	16
OESOPHAGUS	Regulation of myoblast fusion →	+0.116	+0.676	.002	.001	3	15
KIDNEY	Negative regulation of myoblast fusion →	+0.125	+0.542	<.001	<.001	3	15
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.128	+0.542	<.001	<.001	3	15
STOMACH	Negative regulation of mRNA metabolic process →	+0.084	+0.761	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

Negative regulation of proteasomal ubiquitin-dependent protein catabolic process by C17orf113 expression — LUNG_NSCLC_LUSC

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