Across TCGA patient cohorts, C17orf107 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C17orf107-associated genes across cancer lineages are PCNA, EGFR_pY1068, and Notch1. Each is linked with C17orf107 in more than 1 cancer types. Because this analysis shows association rather than direction, both C17orf107-to-partner and partner-to-C17orf107 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C17orf107→partner) and Y-score (partner→C17orf107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.261	+2.321	.004	.033	3	2
UCEC	EGFR_pY1068 →	-0.271	-3.321	.010	.010	3	1
UCEC	Notch1 →	+0.150	+1.700	.011	.044	3	1
UCEC	p21 →	+0.204	+2.820	.012	.035	3	1
UCEC	p62 Lck ligand →	+0.478	+3.459	<.001	.005	3	1
UCEC	p70-S6K_pT389 →	-0.194	-2.999	.016	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

C17orf107 survival (RNA) · tumor vs normal (RNA) · all C17orf107 data types