C16orf97

Across TCGA pan-cancer cohorts, C16orf97 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of C16orf97’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where C16orf97 RNA is repressed in tumor relative to normal tissue. In most cancer types C16orf97 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and LUSC are the cancer types where C16orf97 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C16orf97 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.025	<.001	11	view →
KIRP	All	All	−0.023	<.001	7	view →
LUSC	Male	II,III,IV	+0.007	.039	4	view →
KICH	All	All	+0.208	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

C16orf97–KIRC

Open the KIRC breakdown →