Across TCGA patient cohorts, C16orf96 mutation is significantly associated with the RNA expression of many other genes, with 1,640 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf96-associated genes across cancer lineages are HMGB1P26, BRI3BP, and MAPK12. Each is linked with C16orf96 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf96-to-partner and partner-to-C16orf96 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf96→partner) and Y-score (partner→C16orf96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	HMGB1P26 →	+0.086	+3.791	.008	.002	3	2
UCEC	BRI3BP →	+0.575	+2.010	<.001	<.001	3	2
COAD	MAPK12 →	+0.562	+3.235	.006	.008	3	2
COAD	HCAR1 →	-0.718	-3.405	.008	.005	3	2
COAD	RNU1-70P →	+0.656	+2.250	<.001	.003	3	2
COAD	RN7SKP188 →	+0.050	+4.149	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,640 associations by consensus.

Exploration

C16orf96 survival (RNA) · tumor vs normal (RNA) · all C16orf96 data types