C16orf96

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C16orf96 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf96-associated genes across cancer lineages are Caspase-7-cleavedD198, TFRC, and ATM. Each is linked with C16orf96 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf96-to-partner and partner-to-C16orf96 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf96→partner) and Y-score (partner→C16orf96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCaspase-7-cleavedD198 →+1.382+3.467<.001.00232
UCECTFRC →+0.432+2.115.021.01632
UCECATM →-0.352-1.662.028.01132
UCECDi-Ras3 →-0.146-2.893.005.00132
COADeEF2 →+0.284+2.330.033.02031
COADFOXO3a_pS318_S321 →-0.171-2.296.020.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration