C16orf92

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C16orf92 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,184 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C16orf92-associated GO terms across cancer lineages are Regulation of platelet aggregation, Negative regulation of dendritic cell antigen processing and presentation, and Negative regulation of homotypic cell-cell adhesion. Each is linked with C16orf92 in more than 3 cancer types. Because this analysis shows association rather than direction, both C16orf92-to-partner and partner-to-C16orf92 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of platelet aggregation grouped by C16orf92-low versus C16orf92-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf92→partner) and Y-score (partner→C16orf92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of platelet aggregation →-0.083-0.205.001.00334
BLOOD_LeukemiaNegative regulation of dendritic cell antigen processing and presentation →-1.036-0.067<.001<.00134
BLOOD_LeukemiaNegative regulation of homotypic cell-cell adhesion →-0.112-0.050.001.00934
LUNG_SCLCRegulation of calcium ion transport into cytosol →-0.205-0.177.001.00233
LUNG_SCLCSkeletal myofibril assembly →-0.821-0.264<.001<.00133
BLOOD_LeukemiaRegulation of hemostasis →-0.084-0.070<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,184 associations by consensus.

Regulation of platelet aggregation by C16orf92 expression — LUNG_SCLC

Box plot of Regulation of platelet aggregation in C16orf92-low vs C16orf92-high samples in LUNG_SCLC.

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