C16orf91

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C16orf91 RNA expression is significantly associated with the mutation status of many other genes, with 12,360 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf91-associated genes across cancer lineages are TP53, TTN, and COL11A1. Each is linked with C16orf91 in more than 6 cancer types. Because this analysis shows association rather than direction, both C16orf91-to-partner and partner-to-C16orf91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by C16orf91-low versus C16orf91-high in PRAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf91→partner) and Y-score (partner→C16orf91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PRADTP53 →+1.971+0.411<.001<.00137
UCECTTN →+0.681+0.275<.001<.00135
HNSCCOL11A1 →+3.000+0.262<.001.00234
BLCAPATJ →+2.971+0.426<.001.00534
UCECNFATC4 →+2.258+0.535<.001<.00134
STADXIRP2 →+2.454+0.336<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,360 associations by consensus.

TP53 by C16orf91 expression — PRAD

Box plot of TP53 in C16orf91-low vs C16orf91-high samples in PRAD.

Explore this box plot interactively →

Exploration