C16orf91

Across TCGA patient cohorts, C16orf91 protein abundance is significantly associated with the RNA expression of many other genes, with 3,986 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C16orf91-associated genes across cancer lineages are DNAJA3, LEPROTL1, and PPP3CC. Each is linked with C16orf91 in more than 2 cancer types. Because this analysis shows association rather than direction, both C16orf91-to-partner and partner-to-C16orf91 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C16orf91 versus DNAJA3 in OV, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf91→partner) and Y-score (partner→C16orf91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNAJA3 →	+0.429	+0.585	<.001	<.001	3	3
COAD	LEPROTL1 →	-0.672	-0.878	.002	<.001	3	3
OV	PPP3CC →	-0.445	-0.443	.007	.001	3	3
OV	TRAP1 →	+0.655	+0.618	<.001	<.001	3	3
BRCA	HABP4 →	-0.689	-0.754	.008	.005	3	3
OV	TRAF7 →	+0.550	+0.613	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,986 associations by consensus.

C16orf91 vs DNAJA3 — OV

Explore this scatter interactively →