C16orf91

Across TCGA cell cohorts, C16orf91 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,214 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C16orf91-associated GO terms across cancer lineages are Telomerase RNA stabilization, Protein import into mitochondrial intermembrane space, and Peptidyl-lysine methylation. Each is linked with C16orf91 in more than 13 cancer types. Because this analysis shows association rather than direction, both C16orf91-to-partner and partner-to-C16orf91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomerase RNA stabilization grouped by C16orf91-low versus C16orf91-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf91→partner) and Y-score (partner→C16orf91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Telomerase RNA stabilization →	+0.107	+0.754	<.001	<.001	3	14
BREAST	Protein import into mitochondrial intermembrane space →	+0.113	+0.908	.002	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Peptidyl-lysine methylation →	+0.091	+0.728	.004	.004	3	10
BREAST	Peptidyl-methionine modification →	+0.151	+0.673	.004	.002	3	10
BONE	rRNA modification →	+0.083	+0.601	.004	<.001	3	10
BONE	Termination of RNA polymerase III transcription →	+0.120	+0.464	.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,214 associations by consensus.

Telomerase RNA stabilization by C16orf91 expression — LUNG_NSCLC_LUAD

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