C16orf91

Across TCGA cell cohorts, C16orf91 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C16orf91-associated genes across cancer lineages are SMR3B and MT1HL1. Each is linked with C16orf91 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf91-to-partner and partner-to-C16orf91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMR3B grouped by C16orf91-low versus C16orf91-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf91→partner) and Y-score (partner→C16orf91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SMR3B →	+0.769	+4.467	.004	.004	3	1
LARGE_INTESTINE	MT1HL1 →	+0.087	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SMR3B by C16orf91 expression — LARGE_INTESTINE

Explore this box plot interactively →