Across TCGA patient cohorts, C16orf90 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf90-associated genes across cancer lineages are Heregulin, p62 Lck ligand, and ARID1A. Each is linked with C16orf90 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf90-to-partner and partner-to-C16orf90 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf90→partner) and Y-score (partner→C16orf90) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Heregulin →	-0.203	-3.000	.004	.036	3	1
UCEC	p62 Lck ligand →	+0.477	+3.000	.011	.037	3	1
UCEC	ARID1A →	-0.230	-2.992	.029	.036	3	1
UCEC	C-Raf →	+0.245	+3.000	.003	.037	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

C16orf90 survival (RNA) · tumor vs normal (RNA) · all C16orf90 data types