C16orf89

Across TCGA pan-cancer cohorts, C16orf89 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C16orf89 data layer compared with 21 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C16orf89 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C16orf89 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LUAD, UCEC, and LSCC are the cancer types where C16orf89 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.663	1.000	.007	15	view →
UCEC	OS	Median	All	0.868	1.000	.037	2	view →
LSCC	OS	Quartile	All	1.000	0.678	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C16orf89–LUAD (OS)

Open the LUAD breakdown →