C16orf89

Across TCGA patient cohorts, C16orf89 mutation is significantly associated with the RNA expression of many other genes, with 1,561 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf89-associated genes across cancer lineages are ELAVL4-AS1, SNHG30, and YTHDF3-AS1. Each is linked with C16orf89 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf89-to-partner and partner-to-C16orf89 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELAVL4-AS1 grouped by C16orf89-low versus C16orf89-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf89→partner) and Y-score (partner→C16orf89) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ELAVL4-AS1 →	+0.054	+5.103	.003	.008	3	2
SKCM	SNHG30 →	+0.632	+3.719	.001	<.001	3	2
UCEC	YTHDF3-AS1 →	+0.744	+3.617	<.001	.001	3	2
UCEC	ZNHIT3 →	+0.464	+4.343	.001	<.001	3	2
UCEC	RNA5SP412 →	+0.561	+1.967	<.001	.005	3	2
CESC	RNU6-1214P →	+0.530	+5.306	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,561 associations by consensus.

ELAVL4-AS1 by C16orf89 expression — CESC

Explore this box plot interactively →