C16orf86

Across TCGA patient cohorts, C16orf86 protein abundance is significantly associated with the RNA expression of many other genes, with 7,469 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C16orf86-associated genes across cancer lineages are APBB1, CDKN3, and RRM2. Each is linked with C16orf86 in more than 3 cancer types. Because this analysis shows association rather than direction, both C16orf86-to-partner and partner-to-C16orf86 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C16orf86 versus APBB1 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf86→partner) and Y-score (partner→C16orf86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APBB1 →	+1.428	+0.959	<.001	.002	3	4
LSCC	CDKN3 →	-0.916	-0.357	.002	.004	3	3
BRCA	RRM2 →	-0.902	-0.615	.009	.007	3	3
LSCC	RAB6A →	-0.684	-0.407	.001	<.001	3	3
LSCC	KCMF1 →	-0.657	-0.460	<.001	<.001	3	3
BRCA	BEND3 →	-0.880	-1.017	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,469 associations by consensus.

C16orf86 vs APBB1 — BRCA

Explore this scatter interactively →