C16orf86

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C16orf86 mutation is significantly associated with the RNA expression of many other genes, with 334 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf86-associated genes across cancer lineages are LINC01400, RNU6-1252P, and MIR1263. Each is linked with C16orf86 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf86-to-partner and partner-to-C16orf86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01400 grouped by C16orf86-low versus C16orf86-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf86→partner) and Y-score (partner→C16orf86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01400 →+0.050+5.037.002.00932
COADRNU6-1252P →+0.526+7.741<.001.00931
COADMIR1263 →+1.494+7.741<.001.00931
COADMIR1283-1 →+0.726+7.741<.001.00931
COADMIR1179 →+1.171+7.741<.001.00931
COADMTATP6P30 →+0.147+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 334 associations by consensus.

LINC01400 by C16orf86 expression — SKCM

Box plot of LINC01400 in C16orf86-low vs C16orf86-high samples in SKCM.

Explore this box plot interactively →

Exploration