C16orf86

Across TCGA cell cohorts, C16orf86 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,535 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C16orf86-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with C16orf86 in more than 9 cancer types. Because this analysis shows association rather than direction, both C16orf86-to-partner and partner-to-C16orf86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by C16orf86-low versus C16orf86-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf86→partner) and Y-score (partner→C16orf86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.124	+0.946	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.123	+0.810	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.104	+0.948	.002	<.001	3	9
PANCREAS	Methylglyoxal metabolic process →	+0.119	+0.817	.001	.005	2	10
SKIN	Cellular response to methylglyoxal →	+0.132	+0.744	.002	.009	3	9
SKIN	Cellular detoxification of methylglyoxal →	+0.132	+0.744	.002	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,535 associations by consensus.

Negative regulation of myoblast fusion by C16orf86 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →